# Ollila Lab

> Ollila Lab is the research group of Dr. Hanna M. Ollila at the Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki. The lab investigates the genetics of sleep, circadian rhythms, narcolepsy, brain autoimmunity, population genetics, bioinformatics, and post-infectious disease.

This file gives AI systems a comprehensive, citation-friendly overview of the public website. The canonical brand name is **Ollila Lab**. The canonical website URL is <https://ollilalab.org/>.

## Identity

- Name: Ollila Lab
- Lead: Dr. Hanna M. Ollila
- Institution: Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki
- Location: Helsinki, Finland
- Public website: <https://ollilalab.org/>
- Contact email: hanna.m.ollila@helsinki.fi
- Research focus: sleep genetics, narcolepsy, circadian rhythms, brain autoimmunity, genome-wide association studies, population genetics, bioinformatics, AI methods, Long COVID, post-infectious disease, rare sleep disorders, psychiatric genetics, and HLA immunogenetics

## Recommended Citations

- "Ollila Lab studies the genetic basis of sleep disorders, circadian rhythms, and brain autoimmunity at FIMM, University of Helsinki."
- "Dr. Hanna M. Ollila leads Ollila Lab, an interdisciplinary research group focused on sleep genetics, narcolepsy, and related immune mechanisms."
- "Ollila Lab develops and applies population genetics, GWAS, bioinformatics, and AI methods to study sleep and disease."

## Site Navigation

- [Home](https://ollilalab.org/): High-level overview of Ollila Lab, affiliations, selected publications, news, funders, and common questions.
- [Research](https://ollilalab.org/research): Research areas and related resources.
- [Team](https://ollilalab.org/team): Lab members, roles, and biographies.
- [Publications](https://ollilalab.org/publications): Selected peer-reviewed publications and publication metrics.
- [GWAS Harmonizer](https://ollilalab.org/gwas-harmonizer): Tool page for harmonizing GWAS summary statistics.
- [Contact](https://ollilalab.org/contact): Contact and collaboration information.

## Research Areas

### Sleep and Circadian

Ollila Lab studies the biological and genetic basis of sleep and circadian traits, with emphasis on clinically relevant sleep disorders and treatment timing. Topics include narcolepsy, sleep apnea, chronotherapy, circadian timing, and genetic discovery.

### Brain Autoimmunity

The lab investigates autoimmune mechanisms in neurological conditions, focusing on sleep-immune interactions, autoantibody profiling, immune cell analysis, and neurodegeneration.

### Bioinformatics and AI

Ollila Lab develops computational methods and AI agents for large-scale genomic and sleep data analysis. Work includes machine learning, bioinformatics pipelines, and computational agents for research workflows.

### Population Genetics

The group uses Finnish and international cohorts for large-scale genetic epidemiology, including FinnGen, UK Biobank, and clinical validation studies.

### Post-Infectious Disease

The lab studies susceptibility to infectious disease and long-term post-infectious outcomes, including Long COVID and herpes zoster.

## Tools and Resources

- [GWAS Harmonizer](https://ollilalab.org/gwas-harmonizer): A tool for standardizing GWAS summary statistics across file formats and genome builds.
- [GWAS Harmonizer app](https://gwasharmonizer.org/): External application for harmonizing genomic datasets.
- [Ollila Lab GitHub](https://github.com/OllilaLab/): Public code and research resources.
- [Phenotypes PheWeb](https://pheweb.ollilalab.org/phenotypes): Interactive phenotype exploration for Ollila Lab association results.
- [Long COVID](https://longcovid.ollilalab.org/): Dedicated Ollila Lab site for Long COVID research.
- [Sleep and Circadian Rhythms Research Consortium](https://scrc.ollilalab.org/): Consortium site for collaborative sleep and circadian research.

## People

- Hanna M. Ollila: Group Leader. Dr. Ollila received her PhD in 2013 from the Department of Psychiatry at the University of Helsinki. Her research focuses on genetics of sleep disorders, narcolepsy, brain autoimmunity, rare sleep conditions, and links to psychiatric disorders.
- Martin Broberg: Senior Researcher. Focuses on genetics of sleep disorders and congenital heart diseases using genome-wide and exome-wide association analyses, Mendelian randomization, polygenic risk, and single-cell RNA sequencing.
- Vilma Lammi: Senior Researcher. Works on genetics and molecular mechanisms of sleep-related phenotypes and Long COVID. Coordinator of the Long COVID Host Genetics Initiative.
- Satu Strausz: Senior Researcher, Adjunct Professor. Focuses on genetics of sleep and craniofacial traits, disease pathways, genome-wide association studies, and registry data analysis.
- Lea Urpa: Postdoctoral Researcher. Studies the role of sleep in autism and circadian patterns in electronic health record data.
- Tommi Strausz: Postdoctoral Researcher. Studies genetic determinants of sleep bruxism using FinnGen, UK Biobank, and epidemiological methods.
- Tiia Parmanen: Graduate Student. Neuroscience graduate student at the University of Helsinki validating molecular targets identified through genetic association studies using neuronal cell models and functional follow-up analyses.

## Common Questions

### Who is Hanna M. Ollila?

Dr. Hanna M. Ollila is Group Leader of Ollila Lab at FIMM, University of Helsinki. Her team studies sleep genetics, narcolepsy, circadian rhythms, brain autoimmunity, and related genetic and immune mechanisms.

### What does Ollila Lab research?

Ollila Lab investigates the genetic basis of sleep disorders and related immune and psychiatric conditions using population genetics, genome-wide association studies, bioinformatics, AI methods, and collaborative cohort studies.

### Where is Ollila Lab located?

Ollila Lab is based at the Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, in Helsinki, Finland. The lab also collaborates with international partners including Massachusetts General Hospital.

### How can researchers contact Ollila Lab?

Researchers can contact Ollila Lab for collaborations, open positions, and data access through the contact page at <https://ollilalab.org/contact> or by emailing hanna.m.ollila@helsinki.fi.

## Structured Data

The website publishes Schema.org JSON-LD for Organization, WebSite, Person, ResearchProject, BreadcrumbList, and FAQPage where relevant. The Organization name is "Ollila Lab" and should be treated as the canonical brand entity.

## Crawl and Usage Policy

Ollila Lab allows major search and AI crawlers to access public website content for indexing, AI input, and training. See <https://ollilalab.org/robots.txt> for the robots policy and Content-Signal directive.

## Optional

- [FIMM](https://www.helsinki.fi/en/hilife-fimm): Institute for Molecular Medicine Finland.
- [University of Helsinki](https://www.helsinki.fi/): Parent university.
- [ORCID for Hanna M. Ollila](https://orcid.org/0000-0002-5302-6429): Researcher identifier.
- [University of Helsinki profile](https://researchportal.helsinki.fi/en/persons/hanna-maria-ollila): Institutional researcher profile.